lncRNA Ubr5 promotes BMSCs apoptosis and inhibits their proliferation and osteogenic differentiation in weightless bone loss

BackgroundWeightless bone loss is a common pathological phenomenon in weightless environments, yet its specific molecular mechanism remain incompletely elucidated. The aim of this study was to systematically investigate the differential expression profiles of mRNAs and long noncoding RNAs (lncRNAs)...

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Autors principals:	Dong Wang, Yuan Gao, Yingjun Tan, Na Li, Xi Li, Jiaxiang Li, Yikai Pan, Xingcheng Zhao, Ming Yan, Yongchun Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-04-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	weightless bone loss lncRNA-mRNA coexpression network simulated weightlessness bone marrow mesenchymal stem cells lncRNA Ubr5
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1543929/full
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