Nutritional Stress in Head and Neck Cancer Originating Cell Lines: The Sensitivity of the NRF2-NQO1 Axis

Nutritional stress disturbs the cellular redox-status, which is characterized by the increased generation of reactive oxygen species (ROS). The NRF2-NQO1 axis represents a protective mechanism against ROS. Its strength is cell type-specific. FaDu, Cal 27 and Detroit 562 cells differ with respect to...

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Bibliografische Detailangaben

Hauptverfasser:	Lidija Milković, Marko Tomljanović, Ana Čipak Gašparović, Renata Novak Kujundžić, Dina Šimunić, Paško Konjevoda, Anamarija Mojzeš, Nikola Đaković, Neven Žarković, Koraljka Gall Trošelj
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2019-08-01
Schriftenreihe:	Cells
Schlagworte:	glucose deprivation glutamine deprivation viability proliferation ROS NRF2-NQO1 axis IMR-90 NQO1 transcript variants rs1800566 TP53 mutation
Online-Zugang:	https://www.mdpi.com/2073-4409/8/9/1001
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