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Nutritional Stress in Head and Neck Cancer Originating Cell Lines: The Sensitivity of the NRF2-NQO1 Axis

Nutritional stress disturbs the cellular redox-status, which is characterized by the increased generation of reactive oxygen species (ROS). The NRF2-NQO1 axis represents a protective mechanism against ROS. Its strength is cell type-specific. FaDu, Cal 27 and Detroit 562 cells differ with respect to...

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Principais autores: Lidija Milković, Marko Tomljanović, Ana Čipak Gašparović, Renata Novak Kujundžić, Dina Šimunić, Paško Konjevoda, Anamarija Mojzeš, Nikola Đaković, Neven Žarković, Koraljka Gall Trošelj
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-08-01
Serier:Cells
Fag:
glucose deprivation
glutamine deprivation
viability
proliferation
ROS
NRF2-NQO1 axis
IMR-90
NQO1 transcript variants
rs1800566
TP53 mutation
Online adgang:https://www.mdpi.com/2073-4409/8/9/1001
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