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Selenium nanoparticles alleviate renal ischemia/reperfusion injury by inhibiting ferritinophagy via the XBP1/NCOA4 pathway

Abstract Acute kidney injury (AKI) is closely related to lysosomal dysfunction and ferroptosis in renal tubular epithelial cells (TECs), for which effective treatments are urgently needed. Although selenium nanoparticles (SeNPs) have emerged as promising candidates for AKI therapy, their underlying...

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Hlavní autoři: Zhenying Zuo, Mianna Luo, Zhongyu Liu, Ting Liu, Xi Wang, Xiaorong Huang, Shangmei Li, Hongluan Wu, Qingjun Pan, Tianfeng Chen, Lawei Yang, Hua-Feng Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-07-01
Edice:Cell Communication and Signaling
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On-line přístup:https://doi.org/10.1186/s12964-024-01751-2
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