Selenium nanoparticles alleviate renal ischemia/reperfusion injury by inhibiting ferritinophagy via the XBP1/NCOA4 pathway

Abstract Acute kidney injury (AKI) is closely related to lysosomal dysfunction and ferroptosis in renal tubular epithelial cells (TECs), for which effective treatments are urgently needed. Although selenium nanoparticles (SeNPs) have emerged as promising candidates for AKI therapy, their underlying...

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Principais autores:	Zhenying Zuo, Mianna Luo, Zhongyu Liu, Ting Liu, Xi Wang, Xiaorong Huang, Shangmei Li, Hongluan Wu, Qingjun Pan, Tianfeng Chen, Lawei Yang, Hua-Feng Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-07-01
Series:	Cell Communication and Signaling
Assuntos:	Selenium nanoparticles X-box binding protein 1 Ferritinophagy Ferroptosis Ischemia/reperfusion Acute kidney injury
Acceso en liña:	https://doi.org/10.1186/s12964-024-01751-2
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