Protein C in adult patients with sepsis: from pathophysiology to monitoring and supplementation

Abstract Protein C (PC) plays a crucial role in modulating inflammation and coagulation in sepsis. Its anticoagulant and cytoprotective properties are critical in mitigating sepsis-induced coagulopathy, which is associated with high mortality rates. In sepsis, low levels of PC are associated with an...

詳細記述

書誌詳細

主要な著者:	Irene Coloretti, Antonio Corcione, Gennaro De Pascale, Abele Donati, Francesco Forfori, Marco Marietta, Mauro Panigada, Paolo Simioni, Carlo Tascini, Pierluigi Viale, Massimo Girardis
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-04-01
シリーズ:	Journal of Anesthesia, Analgesia and Critical Care
主題:	Sepsis Septic shock Thrombosis Disseminated intravascular coagulation Activated protein C
オンライン･アクセス:	https://doi.org/10.1186/s44158-025-00243-0
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