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Helicobacter pylori Eradication Modulates Aberrant CpG Island Hypermethylation in Gastric Carcinogenesis

Background : /Aims: Helicobacter pylori infection induces aberrant DNA methylation in gastric mucosa. We evaluated the long-term effect of H. pylori eradication on promotor CpG island hypermethylation in gastric carcinogenesis. Methods : : H. pylori-positive patients with gastric adenoma or early g...

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Principais autores: Jeongmin Choi, Sang Gyun Kim, Byeong Gwan Kim, Seong-Joon Koh, Ji Won Kim, Kook Lae Lee
Format: Artigo
Sprog:Inglês
Udgivet: Jin Publishing & Printing Co. 2016-11-01
Serier:The Korean Journal of Gastroenterology
Fag:
Helicobacter pylori
CpG hypermethylation
p16
CDH1
Carcinogenesis
Online adgang:http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2016.68.5.253
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