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Early Free Light‐Chain Suppression as a Prognostic Marker in Relapsed and Refractory Myeloma Patients Treated With BCMA‐Directed CAR‐T Cells

ABSTRACT Background Relapsed/refractory multiple myeloma (RRMM) remains difficult to treat despite advances in therapy. B‐cell maturation antigen (BCMA)‐directed chimeric antigen receptor T‐cell (CAR‐T) therapies, such as idecabtagene vicleucel (ide‐cel) and ciltacabtagene autoleucel (cilta‐cel), ha...

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Principais autores: Tim Richardson, Hishan Tharmaseelan, Guido Kobbe, Ben‐Niklas Baermann, Tobias A. W. Holderried, Friederike Schmitz, Martina Crysandt, Philipp Gödel, Nathan Wolfensberger, Daniel Schütte, Michael Hallek, Christof Scheid, Udo Holtick
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-10-01
Serier:eJHaem
Fag:
biomarker
CAR‐T cells
multiple myeloma
response assessment
Online adgang:https://doi.org/10.1002/jha2.70139
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