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BCMA-targeted immunotherapy for multiple myeloma

Abstract B cell maturation antigen (BCMA) is a novel treatment target for multiple myeloma (MM) due to its highly selective expression in malignant plasma cells (PCs). Multiple BCMA-targeted therapeutics, including antibody-drug conjugates (ADC), chimeric antigen receptor (CAR)-T cells, and bispecif...

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Principais autores: Bo Yu, Tianbo Jiang, Delong Liu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-09-01
Serier:Journal of Hematology & Oncology
Fag:
B cell maturation antigen
BCMA
Belantamab mafodotin
CAR-T
Antibody-drug conjugate
Bispecific T cell engager
Online adgang:http://link.springer.com/article/10.1186/s13045-020-00962-7
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