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Rhesus Macaque Activating Killer Immunoglobulin-Like Receptors Associate With Fc Receptor Gamma (FCER1G) and Not With DAP12 Adaptor Proteins Resulting in Stabilized Expression and Enabling Signal Transduction

Activating killer cell immunoglobulin-like receptors (KIR) in macaques are thought to be derived by genetic recombination of the region encoding the transmembrane and intracellular part of KIR2DL4 and a KIR3D gene. As a result, all macaque activating KIR possess a positively charged arginine residue...

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Principais autores: Mohammad Zahidul Hasan, Lutz Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-04-01
coleção:Frontiers in Immunology
Assuntos:
adaptor association
Co-immunoprecipitation (co-IP)
rhesus macaque (Macaca mulatta)
DAP12
FCER1G
activating KIR
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.678964/full
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