Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma

Abstract Background CRBP-1, a cytosolic chaperone of vitamin A, is identified in a serious number of cancers; however, its biological role in hepatocellular carcinoma (HCC) needs to be further explored. The aim of our present study is to explore the roles and mechanisms of CRBP-1 in regulating liver...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Xiangye Liu, Wenhua Shan, Tingting Li, Xiaoge Gao, Fanyun Kong, Hongjuan You, Delong Kong, Shuxi Qiao, Renxian Tang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-11-01
coleção:	BMC Cancer
Assuntos:	Cellular retinol binding protein-1 Hepatocellular carcinoma Cancer stemness Retinoic acid Wnt inhibitory factor 1 Wnt/β-catenin signaling pathway
Acesso em linha:	https://doi.org/10.1186/s12885-021-08967-2
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!