Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma

Abstract Background CRBP-1, a cytosolic chaperone of vitamin A, is identified in a serious number of cancers; however, its biological role in hepatocellular carcinoma (HCC) needs to be further explored. The aim of our present study is to explore the roles and mechanisms of CRBP-1 in regulating liver...

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Autori principali:	Xiangye Liu, Wenhua Shan, Tingting Li, Xiaoge Gao, Fanyun Kong, Hongjuan You, Delong Kong, Shuxi Qiao, Renxian Tang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2021-11-01
Serie:	BMC Cancer
Soggetti:	Cellular retinol binding protein-1 Hepatocellular carcinoma Cancer stemness Retinoic acid Wnt inhibitory factor 1 Wnt/β-catenin signaling pathway
Accesso online:	https://doi.org/10.1186/s12885-021-08967-2
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