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Is the Complement Protein C1q a Pro- or Anti-tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas

C1q is the first subcomponent of the classical pathway of the complement system and belongs to the C1q/Tumor Necrosis Factor superfamily. C1q can perform a diverse range of immune and non-immune functions in a complement-dependent as well as -independent manner. Being a pattern recognition molecule...

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Principais autores: Alessandro Mangogna, Chiara Agostinis, Deborah Bonazza, Beatrice Belmonte, Paola Zacchi, Gabriella Zito, Andrea Romano, Fabrizio Zanconati, Giuseppe Ricci, Uday Kishore, Roberta Bulla
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-05-01
Serier:Frontiers in Immunology
Fag:
complement
classical pathway
C1q
tumor
microenvironment
prognosis
Online adgang:https://www.frontiersin.org/article/10.3389/fimmu.2019.00865/full
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