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The Inflammatory Feed-Forward Loop Triggered by the Complement Component C3 as a Potential Target in Endometriosis

The complement system is a major component of humoral innate immunity, acting as a first line of defense against microbes via opsonization and lysis of pathogens. However, novel roles of the complement system in inflammatory and immunological processes, including in cancer, are emerging. Endometrios...

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Principais autores: Chiara Agostinis, Sonia Zorzet, Andrea Balduit, Gabriella Zito, Alessandro Mangogna, Paolo Macor, Federico Romano, Miriam Toffoli, Beatrice Belmonte, Gaia Morello, Anna Martorana, Violetta Borelli, Giuseppe Ricci, Uday Kishore, Roberta Bulla
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-08-01
coleção:Frontiers in Immunology
Assuntos:
C3
endometriosis
mast cells
complement system
TNF-α
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.693118/full
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