Glucagon kinetics assessed by mathematical modelling during oral glucose administration in people spanning from normal glucose tolerance to type 2 diabetes

Background/ObjectivesGlucagon is important in the maintenance of glucose homeostasis, with also effects on lipids. In this study, we aimed to apply a recently developed model of glucagon kinetics to determine the sensitivity of glucagon variations (especially, glucagon inhibition) to insulin levels...

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Autores principales:	Francesco Andreozzi, Elettra Mancuso, Mariangela Rubino, Benedetta Salvatori, Micaela Morettini, Giuseppe Monea, Christian Göbl, Gaia Chiara Mannino, Andrea Tura
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-04-01
Colección:	Frontiers in Endocrinology
Materias:	glucagon alpha-cell insulin sensitivity alpha-cell function insulin glucose homeostasis type 2 diabetes
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1376530/full
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