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Channelrhodopsins with distinct chromophores and binding patterns

Abstract Channelrhodopsins are popular optogenetic tools in neuroscience, but remain poorly understood mechanistically. Here we report the cryo-EM structures of channelrhodopsin-2 (ChR2) from Chlamydomonas reinhardtii and H. catenoides kalium channelrhodopsin (KCR1). We show that ChR2 recruits an en...

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Príomhchruthaitheoirí: Yuanyue Shan, Liping Zhao, Meiyu Chen, Xiao Li, Mingfeng Zhang, Duanqing Pei
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2024-08-01
Sraith:Nature Communications
Rochtain ar líne:https://doi.org/10.1038/s41467-024-51811-x
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