Mechanosensitive channels TMEM63A and TMEM63B mediate lung inflation–induced surfactant secretion

Pulmonary surfactant is a lipoprotein complex lining the alveolar surface to decrease the surface tension and facilitate inspiration. Surfactant deficiency is often seen in premature infants and in children and adults with respiratory distress syndrome. Mechanical stretch of alveolar type 2 epitheli...

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Autori principali:	Gui-Lan Chen, Jing-Yi Li, Xin Chen, Jia-Wei Liu, Qian Zhang, Jie-Yu Liu, Jing Wen, Na Wang, Ming Lei, Jun-Peng Wei, Li Yi, Jia-Jia Li, Yu-Peng Ling, He-Qiang Yi, Zhenying Hu, Jingjing Duan, Jin Zhang, Bo Zeng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2024-03-01
Serie:	The Journal of Clinical Investigation
Soggetti:	Pulmonology
Accesso online:	https://doi.org/10.1172/JCI174508
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