Mechanosensitive channels TMEM63A and TMEM63B mediate lung inflation–induced surfactant secretion
Pulmonary surfactant is a lipoprotein complex lining the alveolar surface to decrease the surface tension and facilitate inspiration. Surfactant deficiency is often seen in premature infants and in children and adults with respiratory distress syndrome. Mechanical stretch of alveolar type 2 epitheli...
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| Principais autores: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2024-03-01
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| Colecção: | The Journal of Clinical Investigation |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1172/JCI174508 |
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