Epidemiology of cryptococcal meningitis and fluconazole heteroresistance in Cryptococcus neoformans isolates from a teaching hospital in southwestern China

ABSTRACT Cryptococcal meningitis (CM), a common and serious opportunistic infection mostly caused by Cryptococcus neoformans, is primarily treated with fluconazole. Nevertheless, Cryptococcus neoformans strains that undergo repeated exposure to azoles can gradually acquire heteroresistance to flucon...

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Autores principales:	Yunfei Huang, Yongqi Zhang, Shuangshuang Yang, Hongling Lu, Hanbing Yu, Xingyue Wang, Xiaojiong Jia, Dijiao Tang, Linhong Wu, Shifeng Huang, Ping Yang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2024-08-01
Colección:	Microbiology Spectrum
Materias:	cryptococcal meningitis Cryptococcus neoformans fluconazole heteroresistance antifungal susceptibility
Acceso en línea:	https://journals.asm.org/doi/10.1128/spectrum.00725-24
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