Epidemiology of cryptococcal meningitis and fluconazole heteroresistance in Cryptococcus neoformans isolates from a teaching hospital in southwestern China

ABSTRACT Cryptococcal meningitis (CM), a common and serious opportunistic infection mostly caused by Cryptococcus neoformans, is primarily treated with fluconazole. Nevertheless, Cryptococcus neoformans strains that undergo repeated exposure to azoles can gradually acquire heteroresistance to flucon...

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Autors principals:	Yunfei Huang, Yongqi Zhang, Shuangshuang Yang, Hongling Lu, Hanbing Yu, Xingyue Wang, Xiaojiong Jia, Dijiao Tang, Linhong Wu, Shifeng Huang, Ping Yang
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2024-08-01
Col·lecció:	Microbiology Spectrum
Matèries:	cryptococcal meningitis Cryptococcus neoformans fluconazole heteroresistance antifungal susceptibility
Accés en línia:	https://journals.asm.org/doi/10.1128/spectrum.00725-24
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