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Schlafen-5 inhibits LINE-1 retrotransposition

Summary: Long interspersed element 1 (LINE-1) is the only currently known active autonomous transposon in humans, and its retrotransposition may cause deleterious effects on the structure and function of host cell genomes and result in sporadic genetic diseases. Host cells therefore developed defens...

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Wedi'i Gadw mewn:
Prif Awduron: Jiwei Ding, Shujie Wang, Qipeng Liu, Yuqing Duan, Tingting Cheng, Zhongjie Ye, Zhanding Cui, Ao Zhang, Qiuyu Liu, Zixiong Zhang, Ning Zhang, Qian Liu, Ni An, Jianyuan Zhao, Dongrong Yi, Quanjie Li, Jing Wang, Yongxin Zhang, Ling Ma, Saisai Guo, Jinhui Wang, Chen Liang, Jinming Zhou, Shan Cen, Xiaoyu Li
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2023-10-01
Cyfres:iScience
Pynciau:
Molecular biology
Molecular genetics
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S258900422302045X
Tagiau: Ychwanegu Tag
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