Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously expressed on the surface of mammalian cells. Owing to its high negatively charged property, heparan sulfate (HS) on the surface...

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Autori principali:	Jiyuan Yang, Yuefan Song, Weihua Jin, Ke Xia, Grace C. Burnett, Wanjin Qiao, John T. Bates, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, Robert J. Linhardt, Jonathan S. Dordick, Fuming Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-02-01
Serie:	Viruses
Soggetti:	HSPGs heparin MERS-CoV sulfated glycans surface plasmon resonance
Accesso online:	https://www.mdpi.com/1999-4915/16/2/237
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