Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously expressed on the surface of mammalian cells. Owing to its high negatively charged property, heparan sulfate (HS) on the surface...

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Bibliografiske detaljer

Principais autores:	Jiyuan Yang, Yuefan Song, Weihua Jin, Ke Xia, Grace C. Burnett, Wanjin Qiao, John T. Bates, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, Robert J. Linhardt, Jonathan S. Dordick, Fuming Zhang
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2024-02-01
Serier:	Viruses
Fag:	HSPGs heparin MERS-CoV sulfated glycans surface plasmon resonance
Online adgang:	https://www.mdpi.com/1999-4915/16/2/237
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