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NEXN protects against vascular calcification by promoting SERCA2 SUMOylation and stabilization

Abstract Vascular calcification, a key risk factor for cardiovascular diseases, is driven by the phenotypic transition of vascular smooth muscle cells from a contractile to an osteogenic phenotype. NEXN, a protein highly associated with heart function, has also been implicated as a potential suscept...

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מידע ביבליוגרפי
Principais autores: Wenjie Guo, Wenjing Guo, Boliang Chen, Zexuan Lin, Zhuohua Wen, Jiamin Ye, Wei Feng, Xin Feng, Jianyun Yan, Pingzhen Yang, Kunfu Ouyang, Yifei Li, Hanyan Yang, Caiwen Ou, Canzhao Liu
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2025-08-01
סדרה:Nature Communications
גישה מקוונת:https://doi.org/10.1038/s41467-025-63462-7
תגים: הוספת תג
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