NEXN protects against vascular calcification by promoting SERCA2 SUMOylation and stabilization
Abstract Vascular calcification, a key risk factor for cardiovascular diseases, is driven by the phenotypic transition of vascular smooth muscle cells from a contractile to an osteogenic phenotype. NEXN, a protein highly associated with heart function, has also been implicated as a potential suscept...
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| Главные авторы: | , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Portfolio
2025-08-01
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| Серии: | Nature Communications |
| Online-ссылка: | https://doi.org/10.1038/s41467-025-63462-7 |
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