Differential chromatin accessibility landscape of gain-of-function mutant p53 tumours
Abstract Background Mutations in TP53 not only affect its tumour suppressor activity but also exerts oncogenic gain-of-function activity. While the genome-wide mutant p53 binding sites have been identified in cancer cell lines, the chromatin accessibility landscape driven by mutant p53 in primary tu...
Kaydedildi:
| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2021-06-01
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| Seri Bilgileri: | BMC Cancer |
| Konular: | |
| Online Erişim: | https://doi.org/10.1186/s12885-021-08362-x |
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