The intracerebral injection of Aβ1-42 oligomers does not invariably alter seizure susceptibility in mice

ObjectivesEpileptiform activity and seizures are present in patients with Alzheimer’s disease (AD) and genetic animal models of AD. Amyloid beta 1-42 (Aβ1-42) oligomers are thought to be crucial in AD and can cause neuronal hyperexcitability in vitro. However, it is unclear whether these Aβ1-42 olig...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Maxime Vande Vyver, Louise Daeninck, Gino De Smet, Najat Aourz, Surajit Sahu, Sebastiaan Engelborghs, Kris Pauwels, Dimitri De Bundel, Ilse Smolders
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2023-09-01
Цуврал:	Frontiers in Aging Neuroscience
Нөхцлүүд:	amyloid beta 1-42 oligomer Alzheimer’s disease epilepsy seizure
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1239140/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!