Activation of locus coeruleus heme oxygenase-carbon monoxide pathway promoted an anxiolytic-like effect in rats

The heme oxygenase-carbon monoxide pathway has been shown to play an important role in many physiological processes and is capable of altering nociception modulation in the nervous system by stimulating soluble guanylate cyclase (sGC). In the central nervous system, the locus coeruleus (LC) is known...

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Hlavní autoři:	P.G. Carvalho-Costa, L.G.S. Branco, C.R.A. Leite-Panissi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Associação Brasileira de Divulgação Científica 2016-04-01
Edice:	Brazilian Journal of Medical and Biological Research
Témata:	Heme oxygenase Carbon monoxide Locus coeruleus Anxiety Elevated plus maze, Light/dark box
On-line přístup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500601&tlng=en
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