Activation of locus coeruleus heme oxygenase-carbon monoxide pathway promoted an anxiolytic-like effect in rats

The heme oxygenase-carbon monoxide pathway has been shown to play an important role in many physiological processes and is capable of altering nociception modulation in the nervous system by stimulating soluble guanylate cyclase (sGC). In the central nervous system, the locus coeruleus (LC) is known...

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Autors principals:	P.G. Carvalho-Costa, L.G.S. Branco, C.R.A. Leite-Panissi
Format:	Artigo
Idioma:	Inglês
Publicat:	Associação Brasileira de Divulgação Científica 2016-04-01
Col·lecció:	Brazilian Journal of Medical and Biological Research
Matèries:	Heme oxygenase Carbon monoxide Locus coeruleus Anxiety Elevated plus maze, Light/dark box
Accés en línia:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500601&tlng=en
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