Transcriptomic and metabolomic insights into the synergistic effects of resveratrol and β-hydroxy-β-methylbutyric acid on hepatic function under varying protein diets in Tibetan sheep

BackgroundIncreasing evidence indicated resveratrol (RES) and β-hydroxy-β-methylbutyric acid (HMB) regulated several biological processes via modulating gene expression. This study employed transcriptomic and metabolomic analyses to investigate the impact of RES and HMB supplementation, in combinati...

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Autori principali:	Yu Zhang, Kaina Zhu, Fengshuo Zhang, Zhenling Wu, Shengzhen Hou, Linsheng Gui
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-07-01
Serie:	Frontiers in Nutrition
Soggetti:	resveratrol β-hydroxy-β-methylbutyric acid Tibetan sheep liver transcriptome metabolome
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnut.2025.1614114/full
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