Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes—A More Selective Anticancer Treatment?

Based on their drug delivery properties and activity against tumors, we combined PAMAM dendrimers with various platinum(IV) complexes in order to provide an improved approach of anticancer treatment. Platinum(IV) complexes were linked to terminal NH₂ moieties of PAMAM dendrimers of genera...

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Auteurs principaux:	Yvonne Lerchbammer-Kreith, Michaela Hejl, Petra Vician, Michael A. Jakupec, Walter Berger, Mathea S. Galanski, Bernhard K. Keppler
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2023-05-01
Collection:	Pharmaceutics
Sujets:	platinum(IV) complexes PAMAM dendrimers anticancer drug delivery
Accès en ligne:	https://www.mdpi.com/1999-4923/15/5/1515
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