Increased Regulatory T Cells in Peripheral Blood of Acute Myeloid Leukemia Patients Rely on Tumor Necrosis Factor (TNF)-α–TNF Receptor-2 Pathway

Acute myeloid leukemia (AML) harbors an immune suppression environment, featured by increased regulatory T cells (Tregs). The expression of tumor necrosis factor receptor-2 (TNFR2) on Tregs could be used to identify the maximally suppressive Treg population, and TNF-α furtherly promoted the expansio...

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Bibliografische Detailangaben

Hauptverfasser:	Min Wang, Chen Zhang, Tian Tian, Teng Zhang, Ruiqing Wang, Fengjiao Han, Chaoqin Zhong, Mingqiang Hua, Daoxin Ma
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2018-06-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	acute myeloid leukemia tumor necrosis factor-α regulatory T cells tumor necrosis factor receptor-2 T helper cells
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01274/full
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