Promoter conservation in HDACs points to functional implications

Abstract Background Histone deacetylases (HDACs) are the proteins responsible for removing the acetyl group from lysine residues of core histones in chromosomes, a crucial component of gene regulation. Eleven known HDACs exist in humans and most other vertebrates. While the basic function of HDACs h...

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Bibliografske podrobnosti

Principais autores:	Toni A. Boltz, Sawsan Khuri, Stefan Wuchty
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2019-07-01
Serija:	BMC Genomics
Teme:	HDAC Promoter analysis TFBS Tissue specificity
Online dostop:	http://link.springer.com/article/10.1186/s12864-019-5973-x
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