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The dynamic conformational landscape of the protein methyltransferase SETD8

Elucidating the conformational heterogeneity of proteins is essential for understanding protein function and developing exogenous ligands. With the rapid development of experimental and computational methods, it is of great interest to integrate these approaches to illuminate the conformational land...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Shi Chen, Rafal P Wiewiora, Fanwang Meng, Nicolas Babault, Anqi Ma, Wenyu Yu, Kun Qian, Hao Hu, Hua Zou, Junyi Wang, Shijie Fan, Gil Blum, Fabio Pittella-Silva, Kyle A Beauchamp, Wolfram Tempel, Hualiang Jiang, Kaixian Chen, Robert J Skene, Yujun George Zheng, Peter J Brown, Jian Jin, Cheng Luo, John D Chodera, Minkui Luo
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2019-05-01
Schriftenreihe:eLife
Schlagworte:
epigenetics
posttranslational modification
enzymology
computational chemistry
Online-Zugang:https://elifesciences.org/articles/45403
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