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The roles of Notch3 on the cell proliferation and apoptosis induced by CHIR99021 in NSCLC cell lines: a functional link between Wnt and Notch signaling pathways.

Wnt and Notch signaling pathways both play essential roles and interact closely in development and carcinogenesis, but their interaction in non-small-cell lung cancer (NSCLC) is poorly unknown. Here we investigated the effects of CHIR99021, a Wnt signaling agonist, or Notch3-shRNA, or the combined a...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chunyan Li, Siyang Zhang, Yao Lu, Ying Zhang, Enhua Wang, Zeshi Cui
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2013-01-01
Rangatū:PLoS ONE
Urunga tuihono:http://europepmc.org/articles/PMC3867546?pdf=render
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