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Absence of FGFR3–TACC3 rearrangement in hematological malignancies with numerical chromosomal alteration

FGFR-TACC, found in different tumor types, is characterized by the fusion of a member of fibroblast grown factor receptor (FGFR) tyrosine kinase (TK) family to a member of the transforming acidic coiled-coil (TACC) proteins. Because chromosome numerical alterations, hallmarks of FGFR–TACC fusions ar...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: C. Banella, M. Ginevrino, G. Catalano, E. Fabiani, G. Falconi, M. Divona, P. Curzi, P. Panetta, M.T. Voso, N.I. Noguera
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Medknow Publications 2021-04-01
Schriftenreihe:Hematology/Oncology and Stem Cell Therapy
Schlagworte:
acute myeloid leukemia
aneuploidy
fgfr3–tacc3
glioblastoma
myelodysplastic syndromes
Online-Zugang:https://journals.lww.com/10.1016/j.hemonc.2020.02.005
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