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Diffuse glioma with FGFR3‐TACC3 fusion in adults is not a homogenous clinicopathological and molecular entity

Abstract Adult diffuse gliomas with FGFR3‐TACC3 (F3T3) fusion are rare and highly heterogeneous central nervous system (CNS) tumors. Current research on the biological behavior of these tumors is limited, especially regarding whether histopathologically low‐grade tumors are indolent or represent ear...

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Principais autores: Xiaoli Su, Jiawen Wu, Pingling Wang, Liwen Hu, Yupeng Chen, Caihong Ren, Fangling Song, Hangrui Lin, Chenlin Ji, Yucheng xie, Xingfu Wang
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-11-01
Serier:The Journal of Pathology: Clinical Research
Fag:
FGFR3–TACC3 fusion
adult diffuse glioma
heterogeneity
classification and grading
molecular characteristics
methylation profiling
Online adgang:https://doi.org/10.1002/2056-4538.70057
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