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Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis

Abstract For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined. Here, we show that polo-like kinase 1 (Plk1), which is instrum...

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Autori principali: Masanori Ikeda, Kozo Tanaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2017-08-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-017-09114-3
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