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Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis

Abstract For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined. Here, we show that polo-like kinase 1 (Plk1), which is instrum...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Masanori Ikeda, Kozo Tanaka
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2017-08-01
Saila:Scientific Reports
Sarrera elektronikoa:https://doi.org/10.1038/s41598-017-09114-3
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