Integrating lymphovascular and perineural invasion into TNM staging: a novel ITNM system for enhanced prognostic stratification in colorectal cancer
BackgroundThe standard TNM staging system for colorectal cancer (CRC) fails to reflect true tumor biology because it ignores key histopathologic features such as lymphovascular and perineural invasion. We therefore developed and validated an “ITNM” classification that folds these two factors into th...
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| Автори: | , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2026-01-01
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| Серія: | Frontiers in Oncology |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fonc.2026.1745324/full |
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