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TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.

Dense core vesicles (DCVs) are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a maturation process through clathrin-mediated membrane remodeling events. This maturation process is required for efficient processing of neuropeptides within DCVs and for...

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Hlavní autoři: Mandy Hannemann, Nikhil Sasidharan, Jan Hegermann, Lena M Kutscher, Sabine Koenig, Stefan Eimer
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS Genetics
On-line přístup:http://europepmc.org/articles/PMC3359978?pdf=render
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