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Somatic evolutionary timings of driver mutations

Abstract Background A unified analysis of DNA sequences from hundreds of tumors concluded that the driver mutations primarily occur in the earliest stages of cancer formation, with relatively few driver mutation events detected in the late-arising subclones. However, emerging evidence from the seque...

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Auteurs principaux: Karen Gomez, Sayaka Miura, Louise A. Huuki, Brianna S. Spell, Jeffrey P. Townsend, Sudhir Kumar
Format: Artigo
Langue:Inglês
Publié: BMC 2018-01-01
Collection:BMC Cancer
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Accès en ligne:http://link.springer.com/article/10.1186/s12885-017-3977-y
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