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A large expert-curated cryo-EM image dataset for machine learning protein particle picking

Abstract Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the structures of biological macromolecular complexes. Picking single-protein particles from cryo-EM micrographs is a crucial step in reconstructing protein structures. However, the widely used template-based particl...

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Autori principali: Ashwin Dhakal, Rajan Gyawali, Liguo Wang, Jianlin Cheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2023-06-01
Serie:Scientific Data
Accesso online:https://doi.org/10.1038/s41597-023-02280-2
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