Auto3DCryoMap: an automated particle alignment approach for 3D cryo-EM density map reconstruction

Abstract Background Cryo-EM data generated by electron tomography (ET) contains images for individual protein particles in different orientations and tilted angles. Individual cryo-EM particles can be aligned to reconstruct a 3D density map of a protein structure. However, low contrast and high nois...

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Detalhes bibliográficos

Principais autores:	Adil Al-Azzawi, Anes Ouadou, Ye Duan, Jianlin Cheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-12-01
coleção:	BMC Bioinformatics
Assuntos:	Cryo-EM 3D density map Particle alignment Particle picking Protein structure
Acesso em linha:	https://doi.org/10.1186/s12859-020-03885-9
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