Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

The gut microbiota influences the development and progression of metabolic diseases partly by metabolism of bile acids (BAs) and modified signaling through the farnesoid X receptor (FXR). In this study, we aimed to determine how the human gut microbiota metabolizes murine BAs and affects FXR signali...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Annika Wahlström, Petia Kovatcheva-Datchary, Marcus Ståhlman, Muhammad-Tanweer Khan, Fredrik Bäckhed, Hanns-Ulrich Marschall
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2017-02-01
Cyfres:	Journal of Lipid Research
Pynciau:	bile acids and salts biosynthesis and metabolism enzyme mechanisms and regulation farnesoid X receptor agonist farnesoid X receptor antagonist gut microbiota
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S002222752031422X
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!