Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

The gut microbiota influences the development and progression of metabolic diseases partly by metabolism of bile acids (BAs) and modified signaling through the farnesoid X receptor (FXR). In this study, we aimed to determine how the human gut microbiota metabolizes murine BAs and affects FXR signali...

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Bibliographic Details

Main Authors:	Annika Wahlström, Petia Kovatcheva-Datchary, Marcus Ståhlman, Muhammad-Tanweer Khan, Fredrik Bäckhed, Hanns-Ulrich Marschall
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2017-02-01
Series:	Journal of Lipid Research
Subjects:	bile acids and salts biosynthesis and metabolism enzyme mechanisms and regulation farnesoid X receptor agonist farnesoid X receptor antagonist gut microbiota
Online Access:	http://www.sciencedirect.com/science/article/pii/S002222752031422X
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