IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer’s disease
Abstract The pathological role of interferon signaling is emerging in neuroinflammatory disorders, yet, the specific role of Interferon Regulatory Factor 3 (IRF3) in neuroinflammation remains poorly understood. Here, we show that global IRF3 deficiency delays TLR4-mediated signaling in microglia and...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2024-08-01
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| Colección: | Journal of Neuroinflammation |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s12974-024-03203-7 |
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