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G-CSF increases calprotectin expression, liver damage and neuroinflammation in a murine model of alcohol-induced ACLF

Background and aims: Granulocyte colony-stimulating factor (G-CSF) has been proposed as a therapeutic option for patients with ACLF, however clinical outcomes are controversial. We aimed at dissecting the role of G-CSF in an alcohol-induced murine model of ACLF.Methods: ACLF was triggered by a singl...

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Principais autores: Martí Ortega-Ribera, Yuan Zhuang, Veronika Brezani, Prashanth Thevkar Nagesh, Radhika S. Joshi, Mrigya Babuta, Yanbo Wang, Gyongyi Szabo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-02-01
coleção:Frontiers in Cell and Developmental Biology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2024.1347395/full
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