Evaluating the immunologically “cold” tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4 + and CD8 + T cells in breast cancer mouse models
Abstract Background Immune-positron emission tomography (PET) imaging with tracers that target CD8 and granzyme B has shown promise in predicting the therapeutic response following immune checkpoint blockade (ICB) in immunologically “hot” tumors. However, immune dynamics in the low T-cell infiltrati...
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| Główni autorzy: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2024-06-01
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| Seria: | Breast Cancer Research |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s13058-024-01844-3 |
| Etykiety: |
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