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Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types.

Existing studies of chromatin conformation have primarily focused on potential enhancers interacting with gene promoters. By contrast, the interactivity of promoters per se, while equally critical to understanding transcriptional control, has been largely unexplored, particularly in a cell type-spec...

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Autori principali: Jia Wen, Taylor M Lagler, Quan Sun, Yuchen Yang, Jiawen Chen, Yuriko Harigaya, Vijay G Sankaran, Ming Hu, Alexander P Reiner, Laura M Raffield, Yun Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2022-01-01
Serie:PLoS Genetics
Accesso online:https://doi.org/10.1371/journal.pgen.1009984
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